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Abstract Background Subarachnoid hemorrhage (SAH) prognosis remains poor. Vasospasm mechanism might be associated with inflammation. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been studied as inflammation markers and prognostic predictors. Objective We aimed to investigate NLR and PLR in admission as predictors of angiographic vasospasm and functional outcome at 6 months. Methods This cohort study included consecutive aneurysmal SAH patients admitted to a tertiary center. Complete blood count was recorded at admission before treatment. White blood cell count, neutrophil count, lymphocyte count, platelet count, NLR, and PLR were collected as independent variables. Vasospasm occurrence-modified Rankin scale (mRS), Glasgow outcome scale (GOS), and Hunt-Hess score at admission and at 6 months were recorded as dependent variables. Multivariable logistic regression models were used to adjust for potential confounding and to assess the independent prognostic value of NLR and PLR at admission. Results A total of 74.1% of the patients were female, with mean age of 55.6 ± 12.4 years. At admission, the median Hunt-Hess score was 2 (interquartile range [IQR] 1), and the median mFisher was 3 (IQR 1). Microsurgical clipping was the treatment for 66.2% of the patients. Angiographic vasospasm incidence was 16.5%. At 6 months, the median GOS was 4 (IQR 0.75), and the median mRS was 3 (IQR 1.5). Twenty-one patients (15.1%) died. Neutrophil-to-lymphocyte ratio and PLR levels did not differ between favorable and unfavorable (mRS > 2 or GOS < 4) functional outcomes. No variables were significantly associated with angiographic vasospasm. Conclusion Admission NLR and PLR presented no value for prediction of functional outcome or angiographic vasospasm risk. Further research is needed in this field.

Resumo Antecedentes O prognóstico da hemorragia subaracnoidea (HSA) permanece ruim. Vasoespasmo pode estar associado à inflamação. Razões neutrófilo-linfócito (NLR) e plaqueta-linfócito (PLR) têm sido estudadas como marcadores de inflamação e prognóstico. Objetivo Investigar NLR e PLR na admissão como preditores de vasoespasmo angiográfico e desfecho aos 6 meses. Métodos Este estudo de coorte incluiu pacientes consecutivos com HSA aneurismática de um centro terciário. Contagem de leucócitos, neutrófilos, linfócitos e plaquetas, proporção de neutrófilos para linfócitos e de plaquetas para linfócitos foram coletados como variáveis independentes. Ocorrência de vasoespasmo, escala de Rankin modificada, escala de desfecho de Glasgow e o escore de Hunt-Hess na admissão e 6 meses após a mesma foram registradas como variáveis dependentes. Modelos de regressão logística multivariável foram usados para ajustar potenciais fatores de confusão e avaliar valor prognóstico independente de NLR e PLR. Resultados Um total de 74,1% pacientes eram do sexo feminino, com idade média de 55,6 ± 12,4 anos. Na admissão, a pontuação média de Hunt-Hess foi de 2 (IQR 1) e a mediana de mFisher foi de 3 (IQR 1). Clipagem microcirúrgica foi o tratamento escolhido para 66,2% dos pacientes. A incidência de vasoespasmo angiográfico foi de 16,5%. Aos 6 meses, a escala de desfecho de Glasgow mediana era 4 (IQR 0,75) e a escala de Rankin modificada mediana era 3 (IQR 1,5). Vinte e um pacientes (15,1%) morreram. Os níveis de NLR e PLR não diferiram entre resultados funcionais favoráveis e desfavoráveis (mRS > 2 ou GOS < 4). Nenhuma variável foi significativamente associada ao vasoespasmo angiográfico. Conclusão Razão neutrófilo-linfócito e a PLR não apresentaram valor preditivo de desfecho funcional ou risco de vasoespasmo angiográfico. Mais pesquisas são necessárias neste campo.

https://doi.org/10.1055/s-0043-1768662

Acoustic Measurements of Speech and Voice in Men with Angle Class II, Division 1, Malocclusion
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Viegas, Flávia

; Camargo, Zuleica

; Viegas, Danieli

; Guimarães, Glaucio Serra

; Luiz, Ronir Raggio

; Ritto, Fabio

; Simões-Zenari, Marcia

; Nemr, Katia

International Archives of Otorhinolaryngology

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Mar 2023, Volume 27 Nº 1 Páginas 10 - 15

Resumo: En | Texto: En | PDF: En

Abstract Introduction The acoustic analysis of speech (measurements of the fundamental frequency and formant frequencies) of different vowels produced by speakers with the Angle class II, division 1, malocclusion can provide information about the relationship between articulatory and phonatory mechanisms in this type of maxillomandibular disproportion. Objectives To investigate acoustic measurements related to the fundamental frequency (F0) and formant frequencies (F1 and F2) of the oral vowels of Brazilian Portuguese (BP) produced by male speakers with Angle class II, division 1, malocclusion (study group) and compare with men with Angle class I malocclusion (control group). Methods In total, 60 men (20 with class II, 40 with class I) aged between 18 and 40 years were included in the study. Measurements of F0, F1 and F2 of the seven oral vowels of BP were estimated from the audio samples containing repetitions of carrier sentences. The statistical analysis was performed using the Student t-test and the effect size was calculated. Results Significant differences (p-values) were detected for F0 values in five vowels ([e], [i], [o], [o] and [u]), and for F1 in vowels [a] and [ɔ], with high levels for class II, division 1. Conclusion Statistical differences were found in the F0 measurements with higher values in five of the seven vowels analysed in subjects with Angle class II, division 1. The formant frequencies showed differences only in F1 in two vowels with higher values in the study group. The data suggest that data on voice and speech production must be included in the protocol’s assessment of patients with malocclusion.

https://doi.org/10.1055/s-0041-1730428

A pandemia da COVID-19 e o trabalho docente: percepções de professores de uma universidade pública no estado de São Paulo, Brasil
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Matias, Aline Bicalho

; Falcão, Márcia Thereza Couto

; Grosseman, Suely

; Germani, Ana Claudia Camargo Gonçalves

; Silva, Andréa Tenório Correia da

Ciência & Saúde Coletiva

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Fev 2023, Volume 28 Nº 2 Páginas 537 - 546

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The COVID-19 pandemic required the restructuring of educational models, including the rapid transition from face-to-face to remote education. The aim of this qualitative research was to understand the effect of the COVID-19 pandemic on undergraduate professors’ work and health at a public university in the state of São Paulo. Semi-structured interviews were conducted with 17 undergraduate faculty of humanities, biological and exact sciences form August to September 2020. The interviews were recorded and transcribed. From the content analysis, four thematic categories emerged: (1) changes in the work routine and their impacts, including adjustment to remote work and the difficulties in establishing boundaries between work and their personal life; (2) changes in the dynamics between faculty and students and the possibility of rethinking teaching practice; (3) the relationship between faculty and the university with emphasis on the decision-making process, support for the transition to remote teaching, and concerns about the quality of teaching; and (4) anguish and fears related to the pandemic that added to the set of work-related stressors. Our findings showed that actions towards the communicational dynamics, as well as actions towards faculties’ mental health should be implemented.

Resumo A pandemia da COVID-19 exigiu a reestruturação dos modelos educacionais nas universidades, incluindo a rápida transição para o ensino remoto. Realizamos uma pesquisa qualitativa com o objetivo de compreender a percepção de professores universitários sobre os efeitos da pandemia da COVID-19 para a rotina de trabalho e para a saúde dos docentes de uma universidade pública no estado de São Paulo. Foram realizadas entrevistas semiestruturadas com 17 docentes de cursos de graduação das ciências humanas, biológicas e exatas, entre agosto e setembro de 2020. As entrevistas foram gravadas e transcritas na íntegra. Da análise de conteúdo, quatro categorias temáticas emergiram: (1) mudanças na rotina de trabalho e seus impactos, incluindo a adaptação ao trabalho remoto e dificuldade em estabelecer limites entre trabalho e rotina pessoal; (2) alterações na dinâmica entre professor/alunos e possibilidade de repensar a prática docente; (3) relação dos docentes com a universidade, o processo de tomada de decisões, suporte para a transição ao ensino remoto e preocupações com a qualidade do ensino; e (4) angústias e medos relacionamos à pandemia que se somaram aos estressores do trabalho. Os resultados ressaltam a necessidade de ações direcionadas à gestão educacional, às dinâmicas comunicacionais e à saúde mental.

https://doi.org/10.1590/1413-81232023282.11972022

A pandemia da COVID-19 e o trabalho docente: percepções de professores de uma universidade pública no estado de São Paulo, Brasil
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Matias, Aline Bicalho

; Falcão, Márcia Thereza Couto

; Grosseman, Suely

; Germani, Ana Claudia Camargo Gonçalves

; Silva, Andréa Tenório Correia da

Ciência & Saúde Coletiva

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2023, Volume 28 Nº 2 Páginas 537 - 546

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232023282.11972022

Indicators for evaluation of model performance: irrigation hydraulics applications
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Sobenko, Luiz Ricardo

; Pimenta, Bruna Dalcin

; Camargo, Antonio Pires de

; Robaina, Adroaldo Dias

; Peiter, Marcia Xavier

; Frizzone, José Antonio

Acta Scientiarum. Agronomy

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2023, Volume 45 elocation e56300

Resumo: En | Texto: En | PDF: En

ABSTRACT. Several mathematical models have been developed for applications in the hydraulics of irrigation systems and several performance indicators of these models are used and suggested by the literature. Thus, the objective of this work was to investigate the performance of statistical indicators for the evaluation of models in irrigation hydraulics. For this, three case studies which represent typical irrigation hydraulics modeling were used to assess the indicators. A set of indicators were analyzed: a) difference-based: mean absolute error, mean square error, root mean square error, scaled root mean square error, and percent mean absolute error; b) efficiency-based: Nash-Sutcliffe and Legates-McCabe; c) correlation coefficient (r); d) coefficient of determination (R2); e) index of agreement index (d); f) Camargo and Sentelhas index (c); and g) graphical methods: regression error characteristic curve based on relative absolute error and 1:1 scatter plot. For the evaluated cases, which are physical phenomena, differentiable indicators are similar measures and it is appropriate to report either or both indices. The assessment of models must also be supported by graphical analysis, which shows the real scenario of errors in the model evaluation processes. Efficiency-based indicators, r, R2, c, and d are not recommended and should be avoided in modeling of irrigation hydraulics.

https://doi.org/10.4025/actasciagron.v45i1.56300

Preparation, Characterization and Stability Study of Eugenol-Loaded Eudragit RS100 Nanocapsules for Dental Sensitivity Reduction
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Vilela, Ana Paula

; Ferreira, Leandro

; Biscaia, Patrícia Bubna

; Silva, Karine Letícia da

; Beltrame, Flávio Luís

; Camargo, Guilherme dos Anjos

; Rezende, Marcia

; Nadal, Jessica Mendes

; Novatski, Andressa

; Manfron, Jane

; Loguercio, Alessandro Dourado

; Farago, Paulo Vitor

Brazilian Archives of Biology and Technology

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2023, Volume 66 Nº spe elocation e23230300

Resumo: En | Texto: En | PDF: En

Abstract Eugenol is a phenolic compound with numerous biological activities. It is widely used in dentistry to treat toothache and pulpitis. In particular, eugenol may be used for tooth whitening procedures to minimize dental sensitivity in patients. However, eugenol has some disadvantages such as its volatility, its photosensitivity, and immediate effect, which can be avoided by using pharmaceutical nanotechnology. The aim of the present study was to obtain, characterize, quantify, and evaluate the physicochemical stability of eugenol-loaded Eudragit RS100 nanocapsules. The nanocapsules (NCs) were prepared by interfacial deposition of the preformed polymer method. The NCs were characterized through morphological and spectroscopic studies. The encapsulation efficiency was achieved by quantifying the non-encapsulated eugenol using a previously developed and validated analytical method. The physicochemical stability of NCs was assessed at predetermined time intervals for 90 days after preparation. The nanocapsules were successfully prepared by the chosen method and had a predominantly spherical shape with a smooth surface. The mean size, the polydispersion index, and the zeta potential were in agreement to literature data. Infrared spectra ensured that the nanoencapsulation process did not result in chemical reactions between the drug and the polymer. The formulations showed encapsulation efficiency higher than 90% and remained stable after 60 days of preparation. Thus, eugenol-loaded Eudragit RS100 nanocapsules may be further considered as an alternative formulation for dental sensitivity in order to provide a controlled release, a decreased toxicity, and a better dental sensitivity relief.

https://doi.org/10.1590/1678-4324-ssbfar-2023230300

Enfrentamento da pandemia de COVID-19 retratado nas Universidades Públicas Federais do Brasil
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Moraes, Juliana Vieira de

; Khalaf, Daiana Kloh

; Freire, Márcia Helena de Souza

; Strapasson, Sabrina

; Mendonça, Roseli Camargo

Acta Paulista de Enfermagem

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2023, Volume 36 elocation eAPE00401

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Objective The present study aimed to identify the health measures adopted by federal public universities in the context of the COVID-19 pandemic. Methods This is a qualitative-quantitative, exploratory and descriptive research carried out through documental analysis of protocols, guidelines, ordinances and booklets made in the federal university scope of Brazil. As for the inclusion criteria, documents must be available on the website of each federal university during the collection period and free consultation of the collection on the internet. The collection period was from March 2020 to November 2021. Results We found 51 documents. Northeastern and southeastern universities were responsible for 46.4% of the total publications of federal universities in Brazil. Conclusion Considering the measures adopted by Higher Education Federal Institutions, the congruence in trying to establish standardized routines and procedures that were able to manage and minimize the spread of COVID-19 within the university was noticeable.

Resumen Objetivo El presente estudio tuvo como objetivo identificar las medidas sanitarias adoptadas por las universidades públicas nacionales en el contexto de la pandemia de COVID-19. Métodos Se trata de un estudio cuali-cuantitativo, exploratorio y descriptivo, realizado mediante el análisis documental de los protocolos, directrices, resoluciones y cartillas confeccionadas en el contexto universitario nacional de Brasil. Los criterios de inclusión fueron la disponibilidad del documento en el sitio web de cada universidad nacional en el período de la recopilación y la libre consulta del acervo por internet. El período de recopilación fue de marzo de 2020 a noviembre de 2021. Resultados Se encontraron 51 documentos. Las universidades del nordeste y del sudeste fueron responsables por el 46,4 % de las publicaciones totales de las universidades nacionales de Brasil. Conclusión Ante las medidas adoptadas por las instituciones nacionales de educación superior, se percibió congruencia para intentar establecer rutinas y procedimientos estandarizados que fueran capaces de controlar y minimizar la diseminación de COVID-19 dentro de la universidad.

Resumo Objetivo O presente estudo teve como objetivo identificar as medidas sanitárias adotadas pelas universidades públicas federais no contexto da pandemia da COVID-19. Métodos Trata-se de uma pesquisa quali-quantitativa, exploratória e descritiva feita por meio da análise documental dos protocolos, diretrizes, portarias e cartilhas confeccionadas no âmbito universitário federal do Brasil. Quanto aos critérios de inclusão foram o documento estar disponível no site de cada universidade federal no período da coleta e a livre consulta do acervo pela internet. O período de coleta foi de março de 2020 a novembro de 2021. Resultados Foram encontrados 51 documentos. As universidades do Nordeste e Sudeste foram responsáveis por 46,4% das publicações totais das universidades federais do Brasil. Conclusão Diante das medidas adotadas pelas Instituições Federais de Ensino Superior, foi perceptível a congruência em tentar estabelecer rotinas e procedimentos padronizados que fossem capazes de controlar e minimizar a disseminação da COVID-19 dentro da universidade.

https://doi.org/10.37689/acta-ape/2023ao00401

The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal
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Lamas, Carlos José Einicker

; Fachin, Diego Aguilar

; Falaschi, Rafaela Lopes

; Alcantara, Daniel Máximo Correa de

; Ale-Rocha, Rosaly

; Amorim, Dalton de Souza

; Araújo, Maíra Xavier

; Ascendino, Sharlene

; Baldassio, Letícia

; Bellodi, Carolina Ferraz

; Bravo, Freddy

; Calhau, Julia

; Capellari, Renato Soares

; Carmo-Neto, Antonio Marcelino do

; Cegolin, Bianca Melo

; Couri, Márcia Souto

; Carvalho, Claudio José Barros de

; Dios, Rodrigo de Vilhena Perez

; Falcon, Aida Vanessa Gomez

; Fusari, Livia Maria

; Garcia, Carolina de Almeida

; Gil-Azevedo, Leonardo Henrique

; Gomes, Marina Morim

; Graciolli, Gustavo

; Gudin, Filipe Macedo

; Henriques, Augusto Loureiro

; Krolow, Tiago Kütter

; Mendes, Luanna Layla

; Limeira-de-Oliveira, Francisco

; Maia, Valéria Cid

; Marinoni, Luciane

; Mello, Ramon Luciano

; Mello-Patiu, Cátia Antunes de

; Morales, Mírian Nunes

; Oliveira, Sarah Siqueira

; Patiu, Claudemir

; Proença, Barbara

; Pujol-Luz, Cristiane Vieira de Assis

; Pujol-Luz, José Roberto

; Rafael, José Albertino

; Riccardi, Paula Raile

; Rodrigues, João Paulo Vinicios

; Roque, Fabio de Oliveira

; Sallum, Maria Anice Mureb

; Santis, Marcelo Domingos de

; Santos, Charles Morphy Dias dos

; Santos, Josenilson Rodrigues dos

; Savaris, Marcoandre

; Shimabukuro, Paloma Helena Fernandes

; Silva, Vera Cristina

; Schelesky-Prado, Daniel de Castro

; Silva-Neto, Alberto Moreira da

; Camargo, Alexssandro

; Sousa, Viviane Rodrigues de

; Urso-Guimarães, Maria Virginia

; Wiedenbrug, Sofia

; Yamaguchi, Carolina

; Nihei, Silvio Shigueo

Revista Brasileira de Entomologia

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2023, Volume 67 Nº 4 elocation e20230051

Resumo: En | Texto: En | PDF: En

ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists.

https://doi.org/10.1590/1806-9665-rbent-2023-0051

Role of temporary arterial occlusion in subarachnoid hemorrhage outcomes: a prospective cohort study
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Yoshikawa, Marcia Harumy

; Rabelo, Nícollas Nunes

; Telles, João Paulo Mota

; Pipek, Leonardo Zumerkorn

; Barbosa, Guilherme Bitencourt

; Barbato, Natália Camargo

; Coelho, Antônio Carlos Samaia da Silva

; Teixeira, Manoel Jacobsen

; Figueiredo, Eberval Gadelha

Acta Cirúrgica Brasileira

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2023, Volume 38 elocation e387923

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: Temporary arterial occlusion (TAO) is a widespread practice in the surgical treatment of intracranial aneurysms. This study aimed to investigate TAO’s role during ruptured aneurysm clipping as an independent prognostic factor on short- and long-term outcomes. Methods: This prospective cohort included 180 patients with ruptured intracranial aneurysms and an indication of microsurgical treatment. Patients who died in the first 12 hours after admission were excluded. Results: TAO was associated with intraoperative rupture (IOR) (odds ratio – OR = 10.54; 95% confidence interval – 95%CI 4.72–23.55; p < 0.001) and surgical complications (OR = 2.14; 95%CI 1.11–4.07; p = 0.01). The group with TAO and IOR had no significant difference in clinical (p = 0.06) and surgical (p = 0.94) complications compared to the group that had TAO, but no IOR. Among the 111 patients followed six months after treatment, IOR, number of occlusions, and total time of occlusion were not associated with Glasgow Outcome Scale (GOS) in the follow-up (respectively, p = 0.18, p = 0.30, and p = 0.73). Among patients who underwent TAO, IOR was also not associated with GOS in the follow-up (p = 0.29). Conclusions: TAO was associated with IOR and surgical complications, being the latter independent of IOR occurrence. In long-term analysis, neither TAO nor IOR were associated with poor clinical outcomes.

https://doi.org/10.1590/acb387923

10.

Could outcomes of intracranial aneurysms be better predict using serum creatinine and glomerular filtration rate?
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Rabelo, Nícollas Nunes

; Pipek, Leonardo Zumerkorn

; Nascimento, Rafaela Farias Vidigal

; Telles, João Paulo Mota

; Barbato, Natalia Camargo

; Coelho, Antônio Carlos Samaia da Silva

; Barbosa, Guilherme Bitencourt

; Yoshikawa, Marcia Harumy

; Teixeira, Manoel Jacobsen

; Figueiredo, Eberval Gadelha

Acta Cirúrgica Brasileira

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2022, Volume 37 Nº 1 elocation e370107

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: To analyze the role of serum creatinine levels as a biomarker of intracranial aneurysm outcomes. Methods: This is a prospective analysis of outcomes of patients with intracranial aneurysm. One hundred forty-seven patients with serum creatinine at admission and 6 months follow up were included. Linear and logistic regressions were used to analyze the data. Modified Rankin scale (mRS) was used to assess outcome. Results: Creatinine level was not directly related to aneurysm outcome nor aneurysm rupture (p > 0.05). However, patients with a glomerular filtration rate (GFR) lower than 72.50 mL·min–1 had an odds ratio (OR) of 3.049 (p = 0.006) for worse outcome. Similarly, aneurysm rupture had an OR of 2.957 (p = 0.014) for worse outcomes. Stepwise selection model selected 4 variables for outcomes prediction: serum creatinine, sex, hypertension and treatment. Hypertensive patients had, on average, an increase in 0.588 in mRS (p = 0.022), while treatment with microsurgery had a decrease in 0.555 (p = 0.038). Conclusions: Patients with higher GFR had better outcomes after 6 months. Patients with higher GFR had better outcomes after 6 months. Creatinine presented an indirect role in GFR values and should be included in models for outcome prediction.

https://doi.org/10.1590/acb370107

11.

Novel pulp capping material based on sodium trimetaphosphate: synthesis, characterization, and antimicrobial properties
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Franzin, Nayara Rodrigues Sartori

; Sostena, Michela Melissa Duarte Seixas

; Santos, Alailson Domingos dos

; Moura, Marcia Regina

; Camargo, Emerson Rodrigues de

; Hosida, Thayse Yumi

; Delbem, Alberto Carlos Botazzo

; Moraes, João Carlos Silos

Journal of Applied Oral Science

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2022, Volume 30 elocation e20210483

Resumo: En | Texto: En | PDF: En

Abstract Objectives: To evaluate the mechanical, physicochemical, and antimicrobial properties of four different formulations containing micro- or nanoparticles of sodium trimetaphosphate (mTMP and nTMP, respectively). Methodology: Four experimental groups were used in this investigation: two mTMP groups and two nTMP groups, each containing zirconium oxide (ZrO2), and solution containing either chitosan or titanium oxide (TiO2) nanoparticles (NPs). Setting time, compression resistance, and radiopacity were estimated. The agar diffusion test was used to assess the antimicrobial activity of the formulations against five different microbial strains: Streptococcus mutans, Lactobacillus casei, Actinomyces israelii, Candida albicans, and Enterococcus faecalis. Parametric and nonparametric tests were performed after evaluating homoscedasticity data (p<0.05). Results: From the properties evaluated, nTMP cements required less setting time and showed greater resistance to compression. Cements containing TiO2 showed greater radiopacity for both nTMP and mTMP. All four cement formulations showed antimicrobial activity against S. mutans and L. casei Conclusion: Formulations containing nTMP have shorter setting times and higher compressive strength, and those with TiO2 nanoparticles showed antimicrobial activities. Clinical relevance: The cement containing nTMP, ZrO2, and TiO2 could be an alternative material for protecting the pulp complex.

https://doi.org/10.1590/1678-7757-2021-0483

12.

Comparison of three different strategies to treat sciatic nerve regeneration: an experimental study
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Smaniotto, Pedro Henrique

; Camargo, Cristina Pires

; Kubrusly, Marcia Saldanha

; Gemperli, Rolf

Acta Cirúrgica Brasileira

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2022, Volume 37 Nº 5 elocation e370501

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: To compare the effect of vein conduit filled with adipose tissue stem cells (ASC) on peripheral nerve injury regeneration. Methods: We analyzed 30 male Wistar rats surgically submitted to a 5-mm gap on the sciatic nerve. Then, the animals were divided into three groups: nerve autografting (AG, n=10), autogenous inverted glycerol-conserved vein (VG, n=10), and autogenous inverted glycerol-conserved vein + ASC (VASCG, n=10). The study endpoints were neuromotor functional analysis, gastrocnemius muscle weight, and sciatic nerve graft histomorphometry analysis. In the histologic analysis, we added a control group (naïve nerve). Results: Regarding functional analysis (Walking tract- score), the findings at week 3 showed a difference between the AG and the VG (-96.6 vs. -59.6, p=0.01, respectively) and between the VG and the inverted vein + VASCG (-59.9 vs. -88.92, p=0.02). At week 12, this study showed a difference between the AG and the VG (-64.8 vs. -47.3, p=0.004, respectively), and also a difference between the VG and the VASCG (-47.3 vs. -57.4, p=0.02, respectively). There was no difference in the histomorphometry analysis (nerve diameter, Schwann cells counting). The gastrocnemius muscles on the intervention side were more atrophic when compared to the gastrocnemius muscles on the control side. Conclusions: Our results suggested better functional recovery in the inverted vein group when compared to control group, and inverted vein + ASC group.

https://doi.org/10.1590/acb370501

13.

Viable-transformative inclusion: diverse means of agency by an adolescent with Specific Intellectual Educational Needs (SIEN) and his educators
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Magalhães, Maria Cecília Camargo

; Fidalgo, Sueli Salles

; Carrijo, Viviane Letícia Silva

; Carvalho, Marcia Pereira de

DELTA: Documentação de Estudos em Lingüística Teórica e Aplicada

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2022, Volume 38 Nº 1 elocation 202257174

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Analisando dados de um projeto desenvolvido durante da pandemia da Covid-19, este artigo é motivado pela transformação viável que a história (Freire, 1996) de um aluno com necessidades educacionais intelectuais específicas (NEIE) e a compreensão de educadoras que trabalham com ele têm dessa história possibilitam em direção a uma visão prospectiva de ensino-aprendizagem, que se concentre mais nas possibilidades do que nas determinações - que enfatizariam uma visão linear, bancária de ensino-aprendizagem (Freire, 1970) e desenvolvimento. O trabalho baseia-se em múltiplos fundamentos teóricos, i.e., discussões sobre necessidades educacionais intelectuais específicas (Fidalgo & Carvalho, 2020; Carvalho et al., no prelo; Fidalgo & Magalhães, 2017), abordagem metodológica da pesquisa crítica de colaboração (Magalhães, 2011, 2018; Magalhães & Fidalgo, 2019), multiletramentos (Magalhães & Carrijo, 2018), agência transformadora (Ninin & Magalhães, 2017) - todos organizados com base na Teoria Histórico-Cultural (Vygotsky, 1924-1934/1993).

ABSTRACT Analyzing data from a project carried out during the Covid-19 pandemics, this paper is motivated by the viable transformation that the history of a student with specific intellectual educational needs (SIEN) - and the understanding that the educators working with him have of this history - allow for a prospective view of teaching-learning, that focuses on possibilities rather than the determinations, which would be the emphasis of a more linear, banking view of teaching-learning (Freire, 1970) and development. It is based on multiple theoretical backgrounds, i.e., discussions about specific intellectual educational needs (Fidalgo & Carvalho, 2020; Carvalho et al., in print; Fidalgo & Magalhães, 2017), critical-collaborative research methodology (Magalhães, 2011, 2018; Magalhães & Fidalgo, 2019), multiliteracies (Magalhães & Carrijo, 2019), transformative agency (Ninin & Magalhães, 2017) - all of which are organized within the Cultural-Historical Theory (Vygotsky, 1924-1934/1993).

https://doi.org/10.1590/1678-460x202257174

14.

Programa Personalizado de Atividades (TAP-BR): proposição de uma versão ambulatorial e avaliação dos seus impactos na demência - Estudo piloto
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Francisco, Isabela da Costa

; Pereira, Gabrielle Christine

; Novelli, Marcia Maria Pires Camargo

Cadernos Brasileiros de Terapia Ocupacional

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2022, Volume 30 elocation e3214

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução O Programa Personalizado de Atividades (TAP-BR) é um programa de intervenção em terapia ocupacional que apresenta resultados promissores na redução dos sintomas comportamentais e psicológicos da demência (SCPD). Objetivos Propor adaptações no TAP-BR para a criação de uma versão ambulatorial desse programa e avaliar o impacto e a sua aplicabilidade. Métodos O TAP-BR foi adaptado para uso e aplicação em ambulatório e foi feita a avaliação da aplicabilidade dessa versão a partir da percepção dos estagiários do último ano do curso de graduação em terapia ocupacional e dos cuidadores familiares. O Inventário Neuropsiquiátrico (INP) e a Escala de Depressão, Ansiedade e Estresse (DASS 21) foram utilizados para avaliar o impacto da versão adaptada. Resultados Foram propostas as seguintes alterações no processo de aplicação do TAP-BR em ambulatório: adequações de termos no Manual de Intervenção e na Pasta de Documentação; adequação da avaliação ambiental a ser realizada a partir de entrevista com o cuidador; redução na duração das sessões, de 90 para 60 minutos. Na visão dos estagiários e cuidadores familiares, o programa se apresentou de fácil aplicação. As medidas apontaram que houve melhora no desgaste dos cuidadores em relação aos SCPD dos idosos (Cohen d=0,49) e em seu estado emocional (Cohen d=0,59), principalmente para a variável depressão (Cohen d=0,81). Conclusão A versão ambulatorial do TAP-BR é um programa de fácil aplicação, com impacto positivo na redução dos SCPD nos idosos e melhora no estado emocional dos cuidadores, com ênfase na variável depressão.

Abstract Introduction The Tailored Activity Program (TAP-BR) is an occupational therapy intervention program that presents promising results in reducing the behavioral and psychological symptoms of dementia (BPSD). Objectives To propose adaptations to the TAP-BR to create an outpatient care version of this program and assess its impact and applicability. Methods The TAP-BR was adapted for use and application in an outpatient care setting, and the applicability of this version was assessed according to the perception of occupational therapy interns and family caregivers. The Neuropsychiatric Inventory (NPI) and the Depression, Anxiety and Stress Scale (DASS 21) were used as outcome measures to evaluate the impact of the adapted version. Results The following changes in the application process of the TAP-BR were proposed for its outpatient format: adaptation of terms in the Intervention Manual and in the Documentation Folder; adequacy of the environmental assessment to be carried out based on an interview with the caregiver; reduction in session duration from 90 to 60 min. From the point of view of the interns and family caregivers, the program can be easily applied. The outcome measures showed that there was improvement in caregiver distress in relation to the BPSD of the older persons with dementia (Cohen’s d=0.49) and in their emotional state (Cohen’s d=0.59), especially regarding the variable depression (Cohen’s d=0.81). Conclusion: The outpatient version of TAP-BR can be easily applied, has a positive impact on reducing the BPSD in older people, and improves the emotional state of caregivers, with emphasis on the variable depression.

https://doi.org/10.1590/2526-8910.ctoao245632141

15.

Child and adolescent victims of sexual violence: aspects of physical and emotional development
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Conceição, Marimeire Morais da

; Whitaker, Maria Carolina Ortiz

; Grimaldi, Monaliza Ribeiro Mariano

; Silva, Luana Lima Pereira da

; Silva, Lucinéia Santos da

; Oliveira, Márcia Maria Carneiro

; Camargo, Climene Laura de

Revista Brasileira de Enfermagem

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2022, Volume 75 elocation e20200584

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: identificar a percepção da equipe multiprofissional de saúde sobre os aspectos do desenvolvimento físico e emocional de crianças e adolescentes que sofreram violência sexual. Métodos: estudo qualitativo, realizado com 30 profissionais de saúde em hospital da Bahia, Brasil, entre junho e julho de 2019. Os dados foram coletados a partir de entrevista norteada por questionário semiestruturado. Os resultados foram interpretados conforme o Interacionismo Simbólico. Resultados: algumas crianças violadas sexualmente tinham menos de cinco anos e aspecto saudável, outras portavam deficiências físicas/mentais. Adolescentes vitimizadas estavam em fase pré-púbere, com estrutura corporal frágil, pouco amadurecidas emocionalmente e desconheciam sobre sexualidade. Considerações finais: aspectos físicos e emocionais infantojuvenis vulnerabilizam crianças para a vitimização sexual, pois facilitam o controle e domínio que o agressor necessita ter sobre elas. Como estratégia de proteção, recomenda-se o uso da educação sexual e em saúde atreladas a maior vigilância de familiares, da equipe multiprofissional e educadores.

ABSTRACT Objective: to identify the multidisciplinary health team’s perception on aspects of the physical and emotional development of children and adolescents who have suffered sexual violence. Methods: a qualitative study, carried out with 30 health professionals in a hospital in Bahia, Brazil, between June and July 2019. Data were collected from an interview guided by a semi-structured questionnaire. The results were interpreted according to Symbolic Interactionism. Results: some sexually violated children were under five years old and healthy, others had physical/mental disabilities. Victimized adolescents were in the pre-pubertal phase, with fragile body structure, not emotionally mature and unaware of sexuality. Final considerations: children’s physical and emotional aspects make children vulnerable to sexual victimization, as they facilitate the control and dominion that offenders need to have over them. As a protection strategy, it is recommended using sexual and health education linked to greater surveillance of family members, multidisciplinary team and educators.

RESUMEN Objetivo: identificar la percepción del equipo multiprofesional de salud sobre aspectos del desarrollo físico y emocional de niños y adolescentes que han sufrido violencia sexual. Métodos: estudio cualitativo, realizado con 30 profesionales de la salud en un hospital de Bahía, Brasil, entre junio y julio de 2019. Los datos fueron recolectados a partir de una entrevista guiada por un cuestionario semiestructurado. Los resultados fueron interpretados según la Teoría del Interaccionismo Simbólico. Resultados: algunos niños violados sexualmente tenían menos de cinco años y estaban sanos, otros tenían discapacidades físicas/mentales. Los adolescentes victimizados se encontraban en la fase prepuberal, con una estructura corporal frágil, no madura emocionalmente y desconociendo la sexualidad. Consideraciones finales: los aspectos físicos y emocionales de los niños, niñas y adolescentes hacen que los niños sean vulnerables a la victimización sexual, ya que facilitan el control y dominio que el agresor debe tener sobre ellos. Como estrategia de protección, se recomienda el uso de la educación sexual y en salud ligada a una mayor vigilancia de los familiares, del equipo multidisciplinario y de los educadores.

https://doi.org/10.1590/0034-7167-2020-0584

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